The phenylalanine in aspartame may precipitate the uncontrolled muscle movements of TD. Other Anti-aspartame activists claim there's a link between aspartame and a multitude of ailments, including: cancer seizures headaches depression attention deficit hyperactivity disorder (ADHD) dizziness weight gain birth defects lupus Alzheimer's disease multiple sclerosis (MS) Research is ongoing to confirm or invalidate connections between these ailments and aspartame, but currently there is still inconsistent outcomes in studies. Some research reports increased risk, symptoms or disease acceleration, while others report no negative outcomes with aspartame intake. When it comes to diabetes and weight loss, one of the first steps many people take is to cut empty calories from their diets. This often includes sugar. Aspartame has both pros and cons when considering diabetes and obesity. First, the Mayo Clinic states that, in general, artificial sweeteners may be beneficial for those with diabetes.
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The acceptable daily intake (ADI) recommendations from the FDA and EFSA are: FDA: 50 milligrams per kilogram of body weight EFSA: 40 milligrams per kilogram of body weight A can of diet soda contains about 185 milligrams of aspartame. A 150-pound (68-kilogram) person would have to drink more than 18 cans of soda a day to exceed the FDA daily intake. Alternately, they'd need nearly 15 cans to exceed the EFSA recommendation. However, people who have a condition called phenylketonuria (PKU) shouldn't use aspartame. People who are taking medications for schizophrenia should also avoid aspartame. Phenylketonuria People with PKU have too much phenylalanine in their blood. Phenylalanine is an essential amino acid found in protein sources such as meat, fish, eggs, and dairy products. It's also one of the two ingredients of aspartame. People with this condition aren't able to properly process phenylalanine. If you have this condition, aspartame is highly toxic. Tardive dyskinesia Tardive dyskinesia (TD) is thought to be a side effect of some schizophrenia medications.